Evidently, as demonstrated with the “positive-like” schizophrenia models’ symptoms [8], the triple application would better define the whole NO-system complexity (otherwise, the successful use of either NOS-blocker [12,29,30] or L-arginine [31,32] might disable each other value in the schizophrenia therapy [12,29,30,31,32]). This evidence concerns the gene NOS1 and schizophrenia.