SLC9A1 and chronic kidney disease: However, NHE-1 expression was enhanced in the neuropil at stratum lacunosum-moleculare (CKD 10 wks, F1,8 = 5.79, p < 0.05; one-way ANOVA; Figure 5B, arrow; C), molecular layer (CKD 10 wks, F1,8 = 12.57, p < 0.01; one-way ANOVA; Figure 5B, arrow; D), and hilus (Figure 5B, *) in CKD rats compared with naïve rats.