USP24 promotes cancer malignancy by inducing IL-6 by stabilizing p300 and beta-transducing repeats-containing proteins (β-TrCP) to boost histone-3 acetylation and NF-B while lowering DNA (cytosine-5)-methyltransferase 1 (DNMT1) in M2 macrophages and lung cancer cells [182]. This evidence concerns the gene DNMT1 and cancer.