PPARA and inflammatory bowel disease: However, under LPS stimulation, in addition to CA1 and BAAT, a gene involved in fatty acid biosynthesis and degradation, the PPAR signaling pathway, peroxisome, ferroptosis, thermogenesis, and adipocytokine signaling pathway (ACSL5) as well as the ENPP6 gene involved in ether lipid metabolism, were among the top up- or downregulated DEGs in the IBD intestinal organoids and tumor enteroids (Figure 11 and Table 15).