CDKN1A and central nervous system cancer: In glioma stem cells (GSCs), [184], miR-146b-5p is also a direct regulator of HuR, and its downregulation in glioma promotes HuR expression, which, in turn, negatively regulates the expression of LincRNA-p21, a long intergenic non-coding RNA involved in the inhibition of β-catenin expression and nuclear translocation in GSC [184].