While the median immunoreactivity score (IRS) in non-malignant pancreatic tissue ranged as low as 1.0, the median IRS for nuclear survivin expression in central tumour areas amounted to 3.4, rising along the infiltrative tumour margins (invasion front) to 4.0, and was determined in lymph node metastases to 4.5, respectively (p < 0.001) (Figure 1a and Figure 2a–c). The gene discussed is BIRC5; the disease is neoplasm.