Of these, only residual tumour burden (HR 1.885; 95% CI (1.065–3.161); p = 0.029) (R1) and high nuclear survivin expression (IRS > 4) in the central PDAC tissue areas (HR 1.798; 95% CI (1.037–3.118); p = 0.012) were designated as independent prognostic factors in the multivariate analysis (Table 7, Figure 2f). This evidence concerns the gene BIRC5 and neoplasm.