In order to test the effect of DDR2 and POSTN on tumor metastasis, we used DDR2-expressing (CAF shSCRM) and DDR2-depleted CAFs (CAF shDDR2) as well as DDR2-depleted, periostin-overexpressing (CAF shDDR2 POSTN OE), and transfection control (CAF shDDR2 Empty Vector) CAFs. The gene discussed is DDR2; the disease is neoplasm.