IDH1 and central nervous system cancer: Only 30 cases of gliomas associated to Ollier disease have been reported in the literature, and most of these belong to the pre-molecular era; therefore, only in seven studies [10,14,23,24,30], our own included, for a total of ten patients, the molecular analysis of gliomas has been performed (Table 1): eight of these (80%) presented the IDH1 R132H mutation.