Comparable with our findings in the Panc-1 transplantation model (Figure 1B,C), Ezh2-deficiency did not affect the pancreatic tumor weight of the recipient mice (Figure 1E) and the survival of the Cas9 Ezh2 KO transplanted mice was even reduced compared to Cas9 Ctrl animals (Figure 1F). Here, EZH2 is linked to pancreatic neoplasm.