ALDH1A1 and neoplasm: The Ingenuity Pathway Analysis (IPA) and Gene Ontology (GO) annotations of the differentially expressed genes demonstrated that 974 treatment inhibited a number of key biological processes associated with tumor initiation and stem cells, including the growth of solid tumor, the inflammatory response, the movement of cancer cells, the development of epithelial tissues, and the drug resistance of tumor cells (red and green colors represent upregulated or downregulated genes, respectively), supporting the role of ALDH1A1 in modulating OCSC biology (Figure 4C).