EGFR and adenocarcinoma: Activating mutations in the kinase domain of the gene encoding the epidermal growth factor receptor (EGFR) resulting in a constitutively active receptor, promoting sustained tumor cell growth and metastasis, account for up to 15% of NSCLC cases of the adenocarcinoma type in Caucasians, while the prevalence may be up to four times higher in Asians [2].