Among 303 cases of cirrhosis and 681 cancer cases four ABCB4 variants were identified (c.1865G>A, p.G622E; c.1333_1334delCT, p.L445Gfs*22; c.1529A>G, p.N510S; c.711A>T, p.I237=) associated with these liver-specific traits (Table 2). The gene discussed is ABCB4; the disease is Cirrhosis.