TJP2 and liver cancer: Instead, only a case of TJP2-related HCC was reported in the adult population: a 19-year-old affected by novel homozygous mutation (c.3334C>T, p.Q1112*) developed cirrhosis, variceal bleeding and primary liver cancer: despite receiving variceal endoscopic band ligation and beta-blockers as secondary prophylaxis of variceal bleeding and radiofrequency ablation for the liver tumour, he needed LT later on (Table 2) [75].