When taken separately, metabolic syndrome was associated with ER (PR = 1.12, 95% CI: 1.02–1.24, p = 0.023), PR (PR = 1.21, 95% CI: 1.06–1.37, p = 0.004), or HR positivity (PR = 1.13, 95% CI: 1.02–1.25, p = 0.02) in Mexican Hispanics (Supplementary Table S5). This evidence concerns the gene ESR1 and metabolic syndrome.