TNFRSF1A and nutritional deficiency disease: In turn, independent predictors of a higher risk of severe malnutrition included stage IV disease according to TNM (OR = 2.69; p = 0.0107), excessive alcohol consumption (OR = 3.99, p = 0.0174), and TT genotype of TNFRSF1A gene (OR = 5.05, p = 0.0350).