PTEN and cancer: The overexpression of miR-10b led to greater motility and invasiveness of cancer cell lines via the inhibition of metastasis suppressors, such as homeobox D10 (HOXD10), neurofibromin 1 (NF1), Krüppel-like factor 4 (KLF4), or phosphatase and tensin homolog (PTEN), while the miR-10b silencing led to lower tumor growth in vivo and less invasiveness in vitro [90].