MiR-200a silences yes-associated protein 1 (YAP-1), as well as other proapoptotic genes, such as phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1/NOXA), B-cell lymphoma 2 (Bcl-2) associated X protein (BAX) or Bcl-2-like protein 1 (BCL2L11/BIM), a process that correlates with the higher metastatic potential in breast cancer cells with upregulation of this specific miRNA [95]. Here, PMAIP1 is linked to breast carcinoma.