ERBB2 and breast cancer: Using TCGA-BRCA (n = 1083) and METABRIC (n = 1699) data, high PANX1 expression suggested poor prognosis for basal-like breast cancer in terms of overall survival (OS) (p < 0.05), while not for Luminal A, Luminal B, HER2-enriched, or normal-like subtype (PAM50 algorithm) (Figure 1B and Figure S1A).