PANX1 and breast cancer: To further investigate the role of PANX1 expression in breast cancer, we analyzed TCGA-BRCA and METABRIC transcriptome data and confirmed that PANX1 was highly expressed in the basal-like subtype (TCGA-BRCA (n = 1083) and METABRIC (n = 1699) data, PAM50 algorithm) (Figure 1C,D).