CD274 and neoplasm: Since MDA-MB-231 TNBC cells showed sensitivity to SNS-032 inhibition and an upregulation of PD-L1 by the remaining live cancer cells, we hypothesized that the dead cell debris generated from SNS-032 inhibition could activate anti-tumor immune surveillance and trigger lymphocyte recruitment, whereas PD-L1 upregulation on the surviving TNBC cells could offer a chance of treatment alongside immunotherapy.