This personalization of therapy has led to increased survival in cancer patients; for example, the anti-EGFR antibody Cetuximab used in the treatment of RAS-wildtype EGFR-expressing advanced colorectal cancer shows improved overall (hazard ratio: 0.77) and progression-free survival (hazard ratio: 0.68) compared to standard of care [7]. The gene discussed is EGFR; the disease is cancer.