The closest protein-coding gene to this SNP is CDKN2B (cyclin dependent kinase inhibitor 2B) (Figure 3F) which is adjacent to the tumor suppressor gene CDKN2A (Cyclin-Dependent Kinase 4 Inhibitor A) in a region that is frequently mutated and deleted in a wide variety of tumors (Table 1 and Figure 2). This evidence concerns the gene CDKN2B and neoplasm.