WFDC2 and endometrial cancer: The combined panel of serum and urine CA125 predicted endometrial cancer with an AUC OF 0.92 (95% CI 0.84, 1.00) while the combined panel of serum and urine HE4 predicted endometrial cancer with an AUC of 0.87 (0.78, 0.97, p < 0.001).