Urine HE4 level was significantly elevated in women with endometrial cancer (median HE4 19.3 nm/L (IQR 14.1, 26.3), compared to controls (median HE4 12.4 (IQR 6, 22.2), p = 0.01) (Figure 3). The gene discussed is WFDC2; the disease is endometrial cancer.