Downregulates both cytotoxic inflammatory responses and cell-mediated immune responses [89]Associated with a higher risk for developing gastric carcinoma in H.-pylori-positive patients [90]IL-10 has suppressive effects on inflammation activation [92]Regulates the function of antigen-presenting cells and both the synthesis and expression of macrophages and the pro-inflammatory cytokines produced by T-cells [93]The level of IL-10 is directly dependent on the gastric cancer stage, therefore influencing the prognosis [50]. This evidence concerns the gene IL10 and gastric cancer.