Abbreviations: Retro—retrospective study; Pro—prospective study; Gp A—(group A), acute complicated appendicitis; Gp B—(group B), acute non-complicated appendicitis; CRP—C-reactive protein; WBC—white blood cell count; BE—Base excess; NP—neutrophil percentage; MLR—monocyte-to-lymphocyte ratio; NLR—neutrophil-to-lymphocyte ratio; PLR—platelet-to-lymphocyte ratio; MPV—mean platelet volume; AVP—arginine vasopressin; PC—platelet count; PCT—procalcitonin; DLAC—D-lactate; AST—aspartate aminotransferase; ALT—alanine aminotransferase. Here, ATP5MK is linked to appendicitis.