In a Parkinson’s disease (PD) model induced by 6-hydroxydopamine (6-OHDA), pathogenic oxidative stress increased the negative mTOR regulator tuberous sclerosis complex 2 (TSC2) and increased autophagy in dopaminergic neurons, implicating that mTOR is a potential intervention target for oxidative-stress-induced dysfunctional autophagy in PD [9]. This evidence concerns the gene TSC2 and Parkinson disease.