MAPK8 and Insulin resistance: Moreover, we evaluated the effects of thyroid hormone and vitamin E on the activation of JNK, the expression levels of genes encoding glucose transporters (e.g., Slc2a1 and Slc2a2), the factors involved in hepatic glucose/lipid homeostasis and insulin signalling (e.g., Ppara, Pparg, Cd36, Irs2), as well as Il1b which is strongly related to insulin resistance [20,21,22].