In endothelial dysfunction we can observe the loss of antithrombotic properties of the endothelium, along with the upregulation of adhesion molecules, like VCAM-1, ICAM-1, which enable leukocyte adhesion, i.e., support the priming of monocytes to the vascular wall, which are then further differentiated into foam cells after the accumulation of modified lipoproteins, which is a crucial step in the process of atherogenesis [46,47,48,49,288,289,290]. Here, VCAM1 is linked to endothelial dysfunction.