IL1B and psoriasis: A study using direct brachial venous endothelial sampling demonstrated that psoriasis patients exhibit impaired endothelial cell vascular health manifested as inflammatory transcript upregulation (e.g., IL-1β, VCAM-1, IL-8, CXCL1, ICAM-1, COX-2, and CCL3), which could involve activated platelets, as suggested by Garshick et al. [214].