These findings could be of particular interest with regard to diseases such as psoriasis, in which the expression of TNF-α is enhanced, since sodium enhances the proatherogenic effect of TNF-α on cell adhesion in the bifurcation of carotid arteries (e.g., arterial areas usually prone to atherosclerosis) in ApoE-deficient mice on HS diet compared to those fed a normal-salt diet [67]. This evidence concerns the gene TNF and psoriasis.