FGF21 and hypertensive disorder: In accordance with the results obtained by Lin Jiang et al., the current study presents for the first time the longitudinal profile of FGF-21 in healthy and preeclamptic women, where FGF-21 levels are significantly elevated at each trimester of pregnancy in preeclamptic women compared with normotensive women, results that could correlate FGF-21, hypertension and NEFA during pregnancy [20].