At the same time, fatty acid metabolism seemed to be affected as well, since uptake of long-chain fatty acids (FAs) (as measured by the fluorescent FA analogue Bodipy FL C16, Figure 3D) and the respective FA transporter CD36 (Figure 3E) were both significantly reduced in response to treatment with CLL-EVs. Here, CD36 is linked to B-cell chronic lymphocytic leukemia.