CREB1 and glioblastoma: Bioinformatics predicts that hsa-circ-0008344 may interact with numerous miRNAs, including miR-433-3p and miR-450b-3p, whereas miR-433-3p has been shown to decrease cell proliferation and boost chemosensitivity in glioblastoma by targeting CREB, it is hypothesized that hsa- circ- 0008344 can sponge tumor suppressor miRNAs, resulting in the disinhibition of the expression of particular targeted oncogenic genes, which leads to the progression of glioblastoma.