Hsa-circ-0006168 and IGF1R were increased in human GBM cells and tissues, whilemiR-628-5p was downregulated in the same cells and tissues; blocking hsa-circ-0006168 and increasing miR-628-5p made A172 and LN229 cells less likely to grow and move, as well as less likely to form colonies and become apoptotic. The gene discussed is IGF1R; the disease is glioblastoma.