CBLN1 and myocardial ischemia: For example, a meta-analysis of seven longitudinal studies (involving a total of ~30,000 participants) reported that specific plasma ceramides [especially higher levels of plasma Cer(d18:1/16:0), Cer(d18:1/18:0) and Cer(d18:1/24:1)] were strong predictors of adverse cardiovascular outcomes both in the general population and in patients with established or suspected ischemic heart disease (IHD) [12].