When we analysed the association between p-mTOR and clinic/pathologic characteristics, a significant association was observed between p-mTOR extent score with pattern of tumour invasion when categorised by I vs II + III + IV grades (p = 0.03) and between p-mTOR intensity score expression and number of mitosis (p = 0.005) (Table 2). This evidence concerns the gene MTOR and neoplasm.