In human OSCC, Vicent et al. (2017) analysed the expression of p-S6 in a series of 125 human patients with OSCC and verified expression of p-S6 protein on either serine 235/236 or serine 240/244 in 83% and 88% tumours, respectively, and both of them were inversely and significantly associated with the tumour size and local infiltration, however no associations were found with survival outcomes [53]. The gene discussed is RPS6; the disease is neoplasm.