Interestingly, catalpol, a monoterpene of the iridoid glycoside family described above, was shown to alleviate colitis in mice by inducing SIRT1 expression through inhibition of miR-132 [88], thus suggesting that non-polyphenolic monoterpenes can also modulate miRNAs, directly or indirectly, to increase SIRT1 expression. This evidence concerns the gene SIRT1 and colitis.