It was observed that TGFβ stimulation increased the levels of MnSOD, fibronectin, vimentin, MMP-9, and N-cadherin and decreased the levels of occludin and E-cadherin in colon cancer cells above the basal level, indicating the mesenchymal-phenotype of these cells is promoted by TGFβ. The gene discussed is VIM; the disease is malignant colon neoplasm.