HSP90AA1 and cancer: Hsp90 is overexpressed in many cancers where it plays an important role in promoting carcinogenesis by correctly folding oncogenic client proteins (e.g., c-Raf, Her2, Akt, HIF1, CDK) involved in tumour growth and adhesion, metastasis, neoangiogenesis, invasion and apoptosis [3,4,5,6].