PCDHA6 and Parkinson disease: At the NPC stage, 25 genes involved in cell adhesion were differentially expressed in PD NPCs from which 5 encode for proteins involved in the guidance of migrating neurons and axons during development and synaptic plasticity (TNC (logFC: −1.9285)), promotion of neurite outgrowth (FLRT1 (logFC: 1.50722), binding to alpha-neurexins (NXPH3 (logFC: 1.688257)), and establishment and maintenance of specific neuronal connections in the brain (PCDHA6 (logFC: 3.897926), CDH23 (logFC: 1.497305)) (Figure 3C, Supplementary Table S8).