In addition, the injection of nondiabetic plasma-treated SVFs not only repressed the expression of the diabetes-induced ICAM, FMO3, IL-6, IL-1β, iNOS, TNF-α, and DPP4 expression, but also suppressed the phosphorylation of JNK and NF-κB in the liver of diabetic mice. Here, MAPK8 is linked to diabetes mellitus.