IGHE and allergic disease: Through a multivariate statistical analysis, the present work allowed to formulate hypotheses regarding the various risk factors associated with this non-compliance: Penicillin IgE-mediated allergy, certain types of surgery (colorectal surgery, hip prosthesis surgery, transurethral resection of the prostate) and two anesthesiologists who were frequently associated with transurethral resections of the prostate.