16/48 of these non-coding RNAs (ncRNAs)(AC125807.2, LINC00431, AP001626.1, LINC00858, LINC01234, AL021578.1, ARHGEF26-AS1, LINC-PINT, PAXIP1-AS2,PAXIP1-AS1, FIRRE, SPANXA2-OT1, FMR1-AS1, IRF1-AS1, STAM-AS1, MIR3936HG) are directly linked to several cancers, including ovarian cancer, esophageal cancer, gastric carcinoma, myeloma, non-small cell lung cancer, colon cancer, colorectal cancer, and hepatocellular carcinoma. The gene discussed is IRF1; the disease is esophageal cancer.