IL20RB and nonpapillary renal cell carcinoma: Next, to explore the roles of IL20RB in ccRCC cell proliferation, si-IL20RB was transfected into A498 and RC-2 cells to downregulate the expression of IL20RB. Significant reduction of IL20RB expression was observed in Fig. 6B and D after si-IL20RB transfection (p < 0.001).