Since perturbations in mTOR signaling are implicated in multiple neurodevelopmental, neurodegenerative and psychiatric disorders (Dayas et al., 2012; Kosillo and Bateup, 2021; Lan et al., 2017) that affect dopaminergic function, it is important to understand how mTOR controls DA neuron cytoarchitecture and physiology. This evidence concerns the gene MTOR and psychiatric disorder.