The induction of liver fibrosis by CCl4 caused a significant (P < 0.05) decrease in anti-apoptotic protein Bcl-2 with a marked increase in pro-apoptotic protein Bax and a significant (P < 0.05) increase in the levels of caspase-3 and -9 after 5 and 9 weeks of CCl4 intoxication when compared to the healthy rats. Here, BAX is linked to Hepatic fibrosis.