Instead of CXCR5 expression, Tph cells express chemokine receptors such as CCR2 and CCR5 in RA (3) and CXCR3 (16, 17), CX3CR1 (18), and CCR9 (19, 20) in other diseases including SLE, IgG4-related disease, and Sjögren’s syndrome. The gene discussed is CX3CR1; the disease is immunoglobulin G4-related sclerosing disease.