IL2 and depressive symptom measurement: Studies of adolescent first-episode MDD report decreased levels of IL-2 relative to non-psychiatric controls (Lee et al., 2020) whereas studies of anxiety, OCD, and depression report increased levels of IL-2 (Henje-Blom et al., 2012; Pallavi et al., 2015; Pérez-Sánchez et al., 2018; Simsek et al., 2016).