used a mixed graphene oxide (GO) gold nanostars (GNSs) substrate for ultrasensitive SERS detection of EVs derived from triple-negative breast cancer (TNBC) type MDA-MB-231 cells and HER2(+) type SKBR3 breast cancer cells via their specific fingerprint Raman bands [178] (Figure 5C1). This evidence concerns the gene ERBB2 and breast cancer.