The mutation frequency of CCGs in CRC patients was shown in a horizontal histogram, such as PER3 (5%), ARNTL2 (4%), PER1 (4%), REV1 (4%), TIMELESS (4%), ARNTL (3%), CSNK1D (3%), KLF10 (3%), and NR1D1 (3%) (Figure 1(h)). This evidence concerns the gene TIMELESS and colorectal carcinoma.