It is found that there are 50 potential targets of PLP in allergy (as shown in Table 2), which were imported into the String database to establish PPI (as shown in Fig. 2), among which the top 5 interaction relationships according to the number are: INS, TNF, CAT, MAPK1 and VEGFA (Fig. 3). This evidence concerns the gene MAPK1 and Allergy.