Interestingly, genes upregulated in this category were included in subcategories revolving around cell movement, invasion of cells, and migration of endothelial cells, where particularly interesting were genes like SAA1, ENG, CDH5, PECAM1, DIO2, NOS3, MMP9 being responsible for tumor vascularization process (Fig. 4b). The gene discussed is PECAM1; the disease is neoplasm.