Many of the genes we listed above, have been already associated with tumor vascularization propagation in other types of cancer—PECAM1, ESM1, CD146, CDH5, ENG, ICAM4, PTN, FGF1, ANKRD1, GATA2, KDR, NOS3, SERPINE1, TIE154,55. The gene discussed is NOS3; the disease is neoplasm.