Genes involved in the cell cycle (Rgcc), endothelial cell migration (Fn1, Sparcl1, Mmp12, and Cxcl12), and metabolism (Pparg) were significantly upregulated in injured young ECs compared to uninjured ones, suggesting that vascular remodeling takes place during the early phase of lung fibrosis resolution in young mice. Here, MMP12 is linked to pulmonary fibrosis.