CD4 and laryngotracheoesophageal cleft: We also found that the number of CD127LowCD25High Treg cells was significantly higher in the LC patients than that in the SC patients (P = 0.006), while the CD45+ lymphocytes (P = 0.306) and the CD3+CD4+ T cells (P = 0.871) showed no significant difference (Fig. 2c).