The authors of this review studied the relocation of transmembrane receptors along advecting cell membranes, like for Vascular Endothelial Growth Factor Receptors 2 (VEGFR2) and αvβ3 integrins, by designing chemo-transport-mechanical multi-physics formulations [42,43,44,45] to describe how the mechanical behavior of an endothelial cell (EC) affects receptor dynamics during the early phases of tumor angiogenesis. Here, KDR is linked to neoplasm.