To identify the microRNAs possibly regulating the inflammasome-amyloid associations in AD, we explored the microRNAs semantically linked to the essential genes ("IAAP," "CTSB," "NLRP3", "PYCARD," and "CASP1") identified in the inflammasome-amyloid associations in AD (see case study 1). This evidence concerns the gene CASP1 and Alzheimer disease.