To identify the microRNAs possibly regulating the inflammasome-amyloid associations in AD, we explored the microRNAs semantically linked to the essential genes ("IAAP," "CTSB," "NLRP3", "PYCARD," and "CASP1") identified in the inflammasome-amyloid associations in AD (see case study 1). Here, NLRP3 is linked to Alzheimer disease.