That is, in cell culture, seeding aggregation has been demonstrated for non-prion disease amyloids such as Tau [16–18], α-synuclein [19–21], amyloid-beta (Aβ) [22–24], huntingtin [25, 26], superoxide dismutase 1 (SOD1) [27, 28] or TDP-43 [29, 30]. Here, SOD1 is linked to prion disease.